Ontology highlight
ABSTRACT:
SUBMITTER: Serrano ME
PROVIDER: S-EPMC7497718 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Molecular imaging and biology 20201001 5
<h4>Purpose</h4>The main purpose of this study was to understand how the positron emission tomography (PET) measure of the synaptic vesicle 2A (SV2A) protein varies in vivo during the development of temporal lobe epilepsy (TLE) in the kainic acid rat model.<h4>Procedures</h4>Twenty Sprague Dawley male rats were administered with multiple systemic doses of saline (control group, n = 5) or kainic acid (5 mg/kg/injection, epileptic group, n = 15). Both groups were scanned at the four phases of TLE ...[more]