Ontology highlight
ABSTRACT:
SUBMITTER: Wajda A
PROVIDER: S-EPMC7504141 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Wajda Anna A Łapczuk-Romańska Joanna J Paradowska-Gorycka Agnieszka A
International journal of molecular sciences 20200903 17
Environmental factors contribute to autoimmune disease manifestation, and as regarded today, AhR has become an important factor in studies of immunomodulation. Besides immunological aspects, AhR also plays a role in pharmacological, toxicological and many other physiological processes such as adaptive metabolism. In recent years, epigenetic mechanisms have provided new insight into gene regulation and reveal a new contribution to autoimmune disease pathogenesis. DNA methylation, histone modifica ...[more]