Ontology highlight
ABSTRACT:
SUBMITTER: Legros V
PROVIDER: S-EPMC7508361 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Legros Vincent V Jeannin Patricia P Burlaud-Gaillard Julien J Chaze Thibault T Gianetto Quentin Giai QG Butler-Browne Gillian G Mouly Vincent V Zoladek Jim J Afonso Philippe V PV Gonzàlez Mariela-Natacha MN Matondo Mariette M Riederer Ingo I Roingeard Philippe P Gessain Antoine A Choumet Valérie V Ceccaldi Pierre-Emmanuel PE
PLoS neglected tropical diseases 20200820 8
Muscle cells are potential targets of many arboviruses, such as Ross River, Dengue, Sindbis, and chikungunya viruses, that may be involved in the physiopathological course of the infection. During the recent outbreak of Zika virus (ZIKV), myalgia was one of the most frequently reported symptoms. We investigated the susceptibility of human muscle cells to ZIKV infection. Using an in vitro model of human primary myoblasts that can be differentiated into myotubes, we found that myoblasts can be pro ...[more]