Ontology highlight
ABSTRACT:
SUBMITTER: Seok JH
PROVIDER: S-EPMC7508890 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Scientific reports 20200922 1
Divalent cations Cu<sup>2+</sup> and Zn<sup>2+</sup> can prevent the viral growth in mammalian cells during influenza infection, and viral titers decrease significantly on a copper surface. The underlying mechanisms include DNA damage by radicals, modulation of viral protease, M1 or neuraminidase, and morphological changes in viral particles. However, the molecular mechanisms underlying divalent cation-mediated antiviral activities are unclear. An unexpected observation of this study was that a ...[more]