Ontology highlight
ABSTRACT:
SUBMITTER: Friend NE
PROVIDER: S-EPMC7511337 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Friend Nicole E NE Rioja Ana Y AY Kong Yen P YP Beamish Jeffrey A JA Hong Xiaowei X Habif Julia C JC Bezenah Jonathan R JR Deng Cheri X CX Stegemann Jan P JP Putnam Andrew J AJ
Scientific reports 20200923 1
Revascularization of ischemic tissues is a major barrier to restoring tissue function in many pathologies. Delivery of pro-angiogenic factors has shown some benefit, but it is difficult to recapitulate the complex set of factors required to form stable vasculature. Cell-based therapies and pre-vascularized tissues have shown promise, but the former require time for vascular assembly in situ while the latter require invasive surgery to implant vascularized scaffolds. Here, we developed cell-laden ...[more]