Ontology highlight
ABSTRACT:
SUBMITTER: Bai J
PROVIDER: S-EPMC7514872 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Bai Jun J Gao Jinglong J Mao Zhijun Z Wang Jianhua J Li Jianhui J Li Wensheng W Lei Yu Y Li Shuaishuai S Wu Zhuo Z Tang Chuanning C Jones Lindsey L Ye Hua H Lou Feng F Liu Zhiyuan Z Dong Zhishou Z Guo Baishuai B Huang Xue F XF Chen Si-Yi SY Zhang Enke E
Journal of human genetics 20150702 10
Colorectal cancer (CRC) is widespread with significant mortality. Both inherited and sporadic mutations in various signaling pathways influence the development and progression of the cancer. Identifying genetic mutations in CRC is important for optimal patient treatment and many approaches currently exist to uncover these mutations, including next-generation sequencing (NGS) and commercially available kits. In the present study, we used a semiconductor-based targeted DNA-sequencing approach to s ...[more]