Protease inhibitors, inflammatory markers, and their association with outcome in dogs with naturally occurring acute pancreatitis.
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ABSTRACT:
SUBMITTER: Kuzi S
PROVIDER: S-EPMC7517856 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Publications
Protease inhibitors, inflammatory markers, and their association with outcome in dogs with naturally occurring acute pancreatitis.
Kuzi Sharon S Mazaki-Tovi Michal M Suchodolski Jan S JS Rimer Dar D Lidbury Jonathan A JA Steiner Joerg M JM Buono Agostino A Nivy Ran R Segev Gilad G Aroch Itamar I
Journal of veterinary internal medicine 20200907 5
<h4>Background</h4>Acute pancreatitis (AP) presumably is associated with pancreatic protease activation, protease inhibitor (PI) depletion, and inflammatory mediator secretion.<h4>Objectives</h4>Examine PIs and inflammatory mediator concentrations in dogs with AP and their association with death.<h4>Animals</h4>Thirty-one dogs diagnosed with AP based on clinical signs, ultrasonographic findings, and increased canine pancreatic lipase immunoreactivity (cPLI) and 51 healthy control dogs.<h4>Method ...[more]
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