Ontology highlight
ABSTRACT:
SUBMITTER: Liu W
PROVIDER: S-EPMC7520269 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Liu Wenjie W Li Zhaofeng Z Cai Zhaopeng Z Xie Zhongyu Z Li Jinteng J Li Ming M Cen Shuizhong S Tang Su'an S Zheng Guan G Ye Guiwen G Su Hongjun H Wang Shan S Wang Peng P Shen Huiyong H Wu Yanfeng Y
Journal of cellular and molecular medicine 20200726 17
Human osteoclasts are differentiated from CD14<sup>+</sup> monocytes and are responsible for bone resorption. Long non-coding RNAs (lncRNAs) have been proved to be significantly involved in multiple biologic processes, especially in cell differentiation. However, the effect of lncRNAs in osteoclast differentiation is less appreciated. In our study, RNA sequencing (RNA-seq) was used to identify the expression profiles of lncRNAs and mRNAs in osteoclast differentiation. The results demonstrated th ...[more]