Ontology highlight
ABSTRACT:
SUBMITTER: Suzuki Y
PROVIDER: S-EPMC7522710 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Suzuki Yasutsugu Y Baidaliuk Artem A Miesen Pascal P Frangeul Lionel L Crist Anna B AB Merkling Sarah H SH Fontaine Albin A Lequime Sebastian S Moltini-Conclois Isabelle I Blanc Hervé H van Rij Ronald P RP Lambrechts Louis L Saleh Maria-Carla MC
Current biology : CB 20200716 18
Endogenous viral elements (EVEs) are viral sequences integrated in host genomes. A large number of non-retroviral EVEs was recently detected in Aedes mosquito genomes, leading to the hypothesis that mosquito EVEs may control exogenous infections by closely related viruses. Here, we experimentally investigated the role of an EVE naturally found in Aedes aegypti populations and derived from the widespread insect-specific virus, cell-fusing agent virus (CFAV). Using CRISPR-Cas9 genome editing, we c ...[more]