Differences of DNA methylation patterns in the placenta of large for gestational age infant.
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ABSTRACT:
SUBMITTER: Shen Z
PROVIDER: S-EPMC7523834 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
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Differences of DNA methylation patterns in the placenta of large for gestational age infant.
Shen Zheng Z Tang Yanfei Y Song Yemei Y Shen Wenxia W Zou Chaochun C
Medicine 20200901 39
To investigate the molecular mechanisms of later metabolic health changes in large for gestational age (LGA) newborns by analyzing deoxyribonucleic acid (DNA) methylation patterns in the placenta of LGA and appropriate for gestational age (AGA) newborns.A total of 6 placentas of LGA and 6 placentas of AGA newborns were enrolled as LGA group and AGA group. DNA methylation was analyzed using the Illumina Infinium Human MethylationEPIC BeadChip microarrays and verified via pyrosequencing and revers ...[more]
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2023-07-26 | GSE238155 | GEO