Ontology highlight
ABSTRACT:
SUBMITTER: Schrott R
PROVIDER: S-EPMC7525661 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Schrott Rose R Rajavel Maya M Acharya Kelly K Huang Zhiqing Z Acharya Chaitanya C Hawkey Andrew A Pippen Erica E Lyerly H Kim HK Levin Edward D ED Murphy Susan K SK
Scientific reports 20200929 1
Men consume the most nicotine and cannabis products but impacts on sperm epigenetics are poorly characterized. Evidence suggests that preconception exposure to these drugs alters offspring neurodevelopment. Epigenetics may in part facilitate heritability. We therefore compared effects of exposure to tetrahydrocannabinol (THC) and nicotine on DNA methylation in rat sperm at genes involved in neurodevelopment. Reduced representation bisulfite sequencing data from sperm of rats exposed to THC via o ...[more]