Ontology highlight
ABSTRACT:
SUBMITTER: Kubota Y
PROVIDER: S-EPMC7528104 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Kubota Yasuo Y Seki Masafumi M Kawai Tomoko T Isobe Tomoya T Yoshida Misa M Sekiguchi Masahiro M Kimura Shunsuke S Watanabe Kentaro K Sato-Otsubo Aiko A Yoshida Kenichi K Suzuki Hiromichi H Kataoka Keisuke K Fujii Yoichi Y Shiraishi Yuichi Y Chiba Kenichi K Tanaka Hiroko H Hiwatari Mitsuteru M Oka Akira A Hayashi Yasuhide Y Miyano Satoru S Ogawa Seishi S Hata Kenichiro K Tanaka Yukichi Y Takita Junko J
Communications biology 20200930 1
To elucidate the molecular pathogenesis of pediatric germ cell tumors (GCTs), we performed DNA methylation array analysis, whole transcriptome sequencing, targeted capture sequencing, and single-nucleotide polymorphism array analysis using 51 GCT samples (25 female, 26 male), including 6 germinomas, 2 embryonal carcinomas, 4 immature teratomas, 3 mature teratomas, 30 yolk sac tumors, and 6 mixed germ cell tumors. Among the 51 samples, 11 were from infants, 23 were from young children, and 17 wer ...[more]