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Validation of the 2018 FIGO cervical cancer staging system.


ABSTRACT: OBJECTIVE:To validate the revised 2018 International Federation of Gynecology and Obstetrics (FIGO) staging system for cervical cancer, with a particular focus on stage IB and stage III disease. METHODS:Two retrospective cohort studies were conducted using The Surveillance, Epidemiology, and End Results Program between 1988 and 2014. The stage IB cohort consisted of node-negative FIGO stage IB1 (tumor size <2?cm), IB2 (2-3.9?cm), and IB3 (?4?cm) cervical cancer. The stage III cohort consisted of FIGO stage IIIA, IIIB, and stage IIIC1 (any pelvic nodal metastasis) cervical cancer. Multivariable analysis was performed for cause-specific survival based on cancer stage. RESULTS:In the stage IB cohort (n?=?8909), stage IB1 tumors were more likely to be adenocarcinoma and low-grade compared to other the groups (P?

SUBMITTER: Matsuo K 

PROVIDER: S-EPMC7528458 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature

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Validation of the 2018 FIGO cervical cancer staging system.

Matsuo Koji K   Machida Hiroko H   Mandelbaum Rachel S RS   Konishi Ikuo I   Mikami Mikio M  

Gynecologic oncology 20181030 1


<h4>Objective</h4>To validate the revised 2018 International Federation of Gynecology and Obstetrics (FIGO) staging system for cervical cancer, with a particular focus on stage IB and stage III disease.<h4>Methods</h4>Two retrospective cohort studies were conducted using The Surveillance, Epidemiology, and End Results Program between 1988 and 2014. The stage IB cohort consisted of node-negative FIGO stage IB1 (tumor size <2 cm), IB2 (2-3.9 cm), and IB3 (≥4 cm) cervical cancer. The stage III coho  ...[more]

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