Ontology highlight
ABSTRACT:
SUBMITTER: Mao A
PROVIDER: S-EPMC7532503 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Mao Aihong A Tang Jinzhou J Tang Deping D Wang Fang F Liao Shiqi S Yuan Hongxia H Tian Caiping C Sun Chao C Si Jing J Zhang Hong H Xia Xiaojun X
Journal of Cancer 20200912 21
Radiotherapy is frequently applied for clinically localized prostate cancer while its efficacy could be significantly hindered by radioresistance. MicroRNAs (miRNAs) are important regulators in mediating cellular responses to ionizing radiation (IR), and strongly associate with radiosensitivity in many cancers. In this study, enhancement of radiosensitivity by miR-29b-3p was demonstrated in prostate cancer cell line LNCaP <i>in vitro</i>. Results showed that miR-29b-3p expression was significant ...[more]