Ontology highlight
ABSTRACT:
SUBMITTER: Quan G
PROVIDER: S-EPMC7539401 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Quan Guomei G Xia Pengpeng P Lian Siqi S Wu Yunping Y Zhu Guoqiang G
Veterinary research 20201007 1
Zinc is the second trace element of living organisms after iron. Given its crucial importance, mammalian hosts restrict the bioavailability of Zinc ions (Zn<sup>2+</sup>) to bacterial pathogens. As a countermeasure, pathogens utilize high affinity Zn<sup>2+</sup> transporters, such as ZnuACB to compete with the host for zinc. It is essential for bacteria to maintain zinc homeostasis and thus maintain their physiology and pathogenesis. In an attempt to uncover the zinc transporter in F4<sup>+</su ...[more]