TRIP13 predicts poor prognosis in clear cell renal cell carcinoma.
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ABSTRACT:
SUBMITTER: Kowalewski A
PROVIDER: S-EPMC7539765 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
TRIP13 predicts poor prognosis in clear cell renal cell carcinoma.
Kowalewski Adam A Jaworski Damian D Antosik Paulina P Smolińska Marta M Ligmanowska Joanna J Grzanka Dariusz D Szylberg Łukasz Ł
American journal of cancer research 20200901 9
What is the leading molecular mechanism that causes broad resistance to systemic therapies remains a key question in renal cancer related research. We explored associations of TRIP13 expression with the clinical course using the tissue microarray (TMA). The TMA contained specimens from 87 patients diagnosed with clear cell renal cell carcinoma (ccRCC). We performed immunohistochemistry to investigate TRIP13 protein expression levels. The overall survival (OS) was analyzed using the Kaplan-Meier ...[more]
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