Brain SPECT perfusion and PET metabolism as discordant biomarkers in major depressive disorder.
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ABSTRACT:
SUBMITTER: Tastevin M
PROVIDER: S-EPMC7544792 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Publications
Brain SPECT perfusion and PET metabolism as discordant biomarkers in major depressive disorder.
Tastevin Maud M Boyer Laurent L Korchia Theo T Fond Guillaume G Lançon Christophe C Richieri Raphaëlle R Guedj Eric E
EJNMMI research 20201008 1
<h4>Background</h4>Brain SPECT perfusion and PET metabolism have been, most often interchangeably, proposed to study the underlying pathological process in major depressive disorder (MDD). The objective of this study was to specify similarities and inconsistencies between these two biomarkers according to global characteristics of the disease. We conducted a retrospective study in 16 patients suffering from treatment-resistant MDD who underwent, during the same current episode, a cerebral perfus ...[more]
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