Ontology highlight
ABSTRACT:
SUBMITTER: Liu P
PROVIDER: S-EPMC7544903 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Liu Ping P Chen Bojun B Wang Zhao-Wen ZW
Nature communications 20201008 1
Proper threat-reward decision-making is critical to animal survival. Emerging evidence indicates that the motor system may participate in decision-making but the neural circuit and molecular bases for these functions are little known. We found in C. elegans that GABAergic motor neurons (D-MNs) bias toward the reward behavior in threat-reward decision-making by retrogradely inhibiting a pair of premotor command interneurons, AVA, that control cholinergic motor neurons in the avoidance neural circ ...[more]