LDL-C: lower is better for longer-even at low risk.
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ABSTRACT:
SUBMITTER: Penson PE
PROVIDER: S-EPMC7545575 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Publications
LDL-C: lower is better for longer-even at low risk.
Penson Peter E PE Pirro Matteo M Banach Maciej M
BMC medicine 20201008 1
<h4>Background</h4>Low-density lipoprotein cholesterol (LDL-C) causes atherosclerotic disease, as demonstrated in experimental and epidemiological cohorts, randomised controlled trials, and Mendelian randomisation studies.<h4>Main text</h4>There is considerable inconsistency between existing guidelines as to how to effectively manage patients at low overall risk of cardiovascular disease (CVD) who have persistently elevated levels of LDL-C. We propose a step-by-step practical approach for the ma ...[more]
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