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Epidemiological parameters of COVID-19 and its implication for infectivity among patients in China, 1 January to 11 February 2020.


ABSTRACT: BackgroundThe natural history of disease in patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remained obscure during the early pandemic.AimOur objective was to estimate epidemiological parameters of coronavirus disease (COVID-19) and assess the relative infectivity of the incubation period.MethodsWe estimated the distributions of four epidemiological parameters of SARS-CoV-2 transmission using a large database of COVID-19 cases and potential transmission pairs of cases, and assessed their heterogeneity by demographics, epidemic phase and geographical region. We further calculated the time of peak infectivity and quantified the proportion of secondary infections during the incubation period.ResultsThe median incubation period was 7.2 (95% confidence interval (CI): 6.9?7.5) days. The median serial and generation intervals were similar, 4.7 (95% CI: 4.2?5.3) and 4.6 (95% CI: 4.2?5.1) days, respectively. Paediatric cases?

SUBMITTER: Lu QB 

PROVIDER: S-EPMC7545819 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature

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Epidemiological parameters of COVID-19 and its implication for infectivity among patients in China, 1 January to 11 February 2020.

Lu Qing-Bin QB   Zhang Yong Y   Liu Ming-Jin MJ   Zhang Hai-Yang HY   Jalali Neda N   Zhang An-Ran AR   Li Jia-Chen JC   Zhao Han H   Song Qian-Qian QQ   Zhao Tian-Shuo TS   Zhao Jing J   Liu Han-Yu HY   Du Juan J   Teng Ai-Ying AY   Zhou Zi-Wei ZW   Zhou Shi-Xia SX   Che Tian-Le TL   Wang Tao T   Yang Tong T   Guan Xiu-Gang XG   Peng Xue-Fang XF   Wang Yu-Na YN   Zhang Yuan-Yuan YY   Lv Shou-Ming SM   Liu Bao-Cheng BC   Shi Wen-Qiang WQ   Zhang Xiao-Ai XA   Duan Xiao-Gang XG   Liu Wei W   Yang Yang Y   Fang Li-Qun LQ  

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 20201001 40


BackgroundThe natural history of disease in patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remained obscure during the early pandemic.AimOur objective was to estimate epidemiological parameters of coronavirus disease (COVID-19) and assess the relative infectivity of the incubation period.MethodsWe estimated the distributions of four epidemiological parameters of SARS-CoV-2 transmission using a large database of COVID-19 cases and potential transmission pairs  ...[more]

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