Ontology highlight
ABSTRACT:
SUBMITTER: Suzuki H
PROVIDER: S-EPMC7547101 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Suzuki Hiroshi H Araki Koji K Matsui Toshiyasu T Tanaka Yuya Y Uno Kosuke K Tomifuji Masayuki M Yamashita Taku T Satoh Yasushi Y Kobayashi Yasushi Y Shiotani Akihiro A
Scientific reports 20201009 1
Recurrent laryngeal nerve (RLN) injury, in which hoarseness and dysphagia arise as a result of impaired vocal fold movement, is a serious complication. Misdirected regeneration is an issue for functional regeneration. In this study, we demonstrated the effect of TrkA inhibitors, which blocks the NGF-TrkA pathway that acts on the sensory/automatic nerves thus preventing misdirected regeneration among motor and sensory nerves, and thereby promoting the regeneration of motor neurons to achieve func ...[more]