Ontology highlight
ABSTRACT:
SUBMITTER: Cheng R
PROVIDER: S-EPMC7549091 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Cheng Ruoyu R Fontana Flavia F Xiao Junyuan J Liu Zehua Z Figueiredo Patrícia P Shahbazi Mohammad-Ali MA Wang Shiqi S Jin Jing J Torrieri Giulia G Hirvonen Jouni T JT Zhang Hongbo H Chen Tongtong T Cui Wenguo W Lu Yong Y Santos Hélder A HA
ACS applied materials & interfaces 20200922 40
Recently, there has been an increasing interest for utilizing the host immune system to fight against cancer. Moreover, cancer vaccines, which can stimulate the host immune system to respond to cancer in the long term, are being investigated as a promising approach to induce tumor-specific immunity. In this work, we prepared an effective cancer vaccine (denoted as "vacosome") by reconstructing the cancer cell membrane, monophosphoryl lipid A as a toll-like receptor 4 agonist, and egg phosphatidy ...[more]