Physiological and Race Pace Characteristics of Medium and Low-Level Athens Marathon Runners.
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ABSTRACT:
SUBMITTER: Myrkos A
PROVIDER: S-EPMC7552741 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
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Project description:Background: Beyond the difference in marathon performance when comparing female and male runners, we tested the hypothesis that running strategy does not different according to sex. The goal of the present study is to compare the running strategy between the best female and male marathon performances achieved in the last two years. Methods: Two aspects of the races were analyzed: (i) average speed relative to runner critical speed (CS) with its coefficient of variation and (ii) asymmetry and global tendency of race speed (i.e., the race's Kendall ? ) . Results: The females' best marathons were run at 97.6% ± 3% of CS for the new record (Brigid Kosgei, 2019) and at 96.1% ± 4.4% for the previous record (Paula Radcliffe, 2003). The best male performances (Eliud Kipchoge, 2018 and 2019) were achieved at a lower fraction of CS (94.7% ± 1.7% and 94.1% ± 2.3% in 2018 and 2019, respectively). Eliud Kipchoge (EK) achieved a significant negative split race considering the positive Kendall's ? of pacing (i.e., time over 1 km) ( ? = 0.30; p = 0.007). Furthermore, EK ran more of the average distance below average speed (54% and 55% in 2018 and 2019, respectively), while female runners ran only at 46% below their average speed. Conclusions: The best female and male marathon performances were run differently considering speed time course (i.e., tendency and asymmetry), and fractional use of CS. In addition, this study shows a robust running strategy (or signature) used by EK in two different marathons. Improvement in marathon performance might depend on negative split and asymmetry for female runners, and on higher fractional utilization of CS for male runners.
| S-EPMC7068447 | biostudies-literature
Project description:This study aimed to identify the similarities and differences among half-marathon runners in relation to their performance level. Forty-eight male runners were classified into 4 groups according to their performance level in a half-marathon (min): Group 1 (n = 11, < 70 min), Group 2 (n = 13, < 80 min), Group 3 (n = 13, < 90 min), Group 4 (n = 11, < 105 min). In two separate sessions, training-related, anthropometric, physiological, foot strike pattern and spatio-temporal variables were recorded. Significant differences (p<0.05) between groups (ES = 0.55-3.16) and correlations with performance were obtained (r = 0.34-0.92) in training-related (experience and running distance per week), anthropometric (mass, body mass index and sum of 6 skinfolds), physiological (VO2max, RCT and running economy), foot strike pattern and spatio-temporal variables (contact time, step rate and length). At standardized submaximal speeds (11, 13 and 15 km·h-1), no significant differences between groups were observed in step rate and length, neither in contact time when foot strike pattern was taken into account. In conclusion, apart from training-related, anthropometric and physiological variables, foot strike pattern and step length were the only biomechanical variables sensitive to half-marathon performance, which are essential to achieve high running speeds. However, when foot strike pattern and running speeds were controlled (submaximal test), the spatio-temporal variables were similar. This indicates that foot strike pattern and running speed are responsible for spatio-temporal differences among runners of different performance level.
| S-EPMC5783408 | biostudies-literature
Project description:In recent years, there has been increasing interest in the homeostatic response to extreme exercises, especially in the integrated function of muscle and bone. The aim of this study was to evaluate the effects of a marathon race on selected myokines and sclerostin in 10 male recreational runners (mean age 41 ± 7.7 years). Body composition, bone mineral density (BMD), and the serum concentration of myostatin, irisin, sclerostin, osteoprotegerin (OPG), 25-hydroxyvitamin D (25(OH)D), parathyroid hormone (PTH), high-sensitivity interleukin-6 (hsIL-6), tumor necrosis factor α (TNFα), high-sensitivity C-reactive protein (hsCRP) and myoglobin, were determined 24 h before and 24 h and 72 h after a marathon race. Post-marathon increases were observed in the levels of myostatin (1.2-fold), OPG (1.5-fold), and PTH (1.3-fold), hsIL-6 (1.9-fold), myoglobin (4.1-fold), hsCRP (fivefold), TNFα (2.6-fold), after 24 h; and in myostatin (1.2-fold), irisin (1.1-fold), sclerostin (1.3-fold), OPG (1.3-fold), and PTH (1.4-fold), hsIL-6 (1.4-fold), TNFα (1.9-fold), after 72 h compared to the baseline level. The results show that in response to the marathon run, a complex network of endocrine interactions is initiated. Further research is needed to fully elucidate the long-term impact of prolonged high intensity exercise on the human body.
| S-EPMC7854637 | biostudies-literature
Project description:Introduction:Marathon, as a long-distance aerobic exercise, has become a fashionable or popular sport. However, little is known about the holistic metabolic changes occurring within the serum metabolome of athletes after the completion of a marathon. Objectives:The goal of current study was to have an in-depth understanding of the impact of marathon on human metabolomics as well as the relationships among a variety of metabolites. Methods:The 20 studied subjects were all adult males who participated in a marathon. The serum samples of these participants were collected before and after the marathon and the biochemical metabolites in the serum were identified by an untargeted two-dimensional gas chromatography time-of-flight mass spectrometry. Results:All participants completed the marathon within 3?h. Compared to those before exercise, serum urea and creatine kinase, as well as cortisol, elevated significantly (p?<?0.05), whereas testosterone decreased significantly (p?<?0.01). Metabolomic analysis showed that, compared to those before the competition, metabolites pyruvic acid, glyceric acid, malic acid, cis-aconitic acid, galacturonic acid, methyl fumaric acid, maltotriose, and others increased significantly after the competition (p?<?0.05), but glucosamine and O-succinyl-L-homoserine decreased significantly (p?<?0.05). Amino acid indexes, such as alanine, L-tyrosine and phenylalanine, increased significantly after exercise compared with those before exercise (p?<?0.05), whereas serine, valine and asparagine decreased significantly (p?<?0.05). Lipid metabolism indexes, glycerol, glyceric acid, octanoic acid, and quinic acid increased significantly (p?<?0.05). Theophylline, xanthine and other indicators of caffeine metabolism increased significantly (p?<?0.05). Furthermore, marathon performance, fat percentage, VO2max, and hemoglobin were correlated with the serum metabonomic indicators, so were serum testosterone and cortisol. Conclusion:These results illustrate that the metabolism of glucose and lipid of the athletes was enhanced following the marathon match. In addition, the metabolism of glucosamine was decreased and the metabolism of caffeine was increased. Our data provide new insights for marathon performance and nutritional status.
| S-EPMC7071712 | biostudies-literature
Project description:An ultra-marathon trail (UMT) represents a significant physical and psychological effort. However, little is known about the gene expression response to an UMT although this approach has been explored in shorter races. The objective is to identify the affected pathways in response to an 82km UMT considering a genome-wide analysis. Such response is interpreted as a global effect and as a sum of independent sources identified through an Independent Component Analysis.
2017-06-19 | GSE93945 | GEO
Project description:BACKGROUND:Replication studies are essential for identifying credible associations between alleles and phenotypes. Validation of genotype-phenotype associations in the sports and exercise field is rare. An initial genetic association study suggested that rs1049305 (C > G) in the 3' untranslated region (3'UTR) of the aquaporin-1 (AQP1) gene was associated with marathon running (MR) performance level in Hispanic males. To validate this finding, we conducted a replication analysis in an independent case-control sample of Hispanic male marathon runners (n = 1430; cases n = 713 and controls n = 717). A meta-analysis was utilized to test the extent of the association between the initial results and the present report. It also provided to test the heterogeneity (variation) between the two studies. RESULTS:The replication study showed a statistically significant (p ? 0.05) association between rs1049305 (C > G) of the AQP1 gene and MR performance level. Association test results using a fixed effect model for the combined, original study and the present report, yielded an odds ratio = 1.28, 95% confidence interval = 1.13-1.45, p = 0.0001. The extent of the measures of heterogeneity was Tau-squared = 0, H statistic = 1, I2 statistic = 0, and Cochran's Q test (Q = 0.29; p value 0.59), indicated the variation between studies were due to chance and not to differences in heterogeneity between the two studies. Within the limitations of the present replication, contrast of two studies and its effects on meta-analysis, the findings were robust. CONCLUSION:This study successfully replicated the results of Martínez et al. (Med Sportiva 13:251-5, 2009). The meta-analysis provided further epidemiological credibility for the hypothesis of association between the DNA rs1049305 (C > G) variation in the 3'UTR of the AQP1 gene and MR running performance level in Hispanics male marathon runners. It is not precluded that a linked DNA structure in the surrounding molecular neighborhood could be of influence by been part of the overly complex phenotype of MR performance level.
| S-EPMC7083975 | biostudies-literature
Project description:The purposes of this study were 1) to analyse the different pacing behaviours based on athlete's performance and 2) to determine whether significant differences in each race split and the runner's performance implied different race profiles. A total of 2295 runners, which took part in Berlin's marathon (2017), met the inclusion criteria. 4 different groups were created based on sex and performance. Men: Elite (<02:19:00 h), Top 1 (<02:30:00 h), Top 2 (<02:45:00 h) and Top 3 (<03:00:00 h); women: Elite (02:45:00 h), Top 1 (<03:00:00 h), Top 2 (<03:15:00 h), Top 3 (<03:30:00 h). With the aim of comparing the pacing between sex and performance the average speed was normalized. In men, no statistically significant changes were found between performance group and splits. A large number of significant differences between splits and groups were found amongst women: 5-10 km Top 2 vs Top 3 (P = 0.0178), 10-15 km Top1 vs Top 2 (P = 0.0211), 15-20 km Top1 vs Top 2 (P = 0.0382), 20-21.1 km Elite vs Top 2 (P = 0.0129); Elite vs Top 3 (P = 0.0020); Top1 vs Top 2 (P = 0.0233); Top 1 vs Top 3 (P = 0.0007), 25-30 km Elite vs Top 2 (P = 0.0273); Elite vs Top 3 (P = 0.0156), 30-35 km Elite vs Top 2 (P = 0.0096); Top 1 vs Top 2 (P = 0.0198); Top2 vs Top3 (P = 0.0069). In men there were little significant differences based on athletes' performance which implied a similar pacing behaviour. Women presented numerous differences based on their performance which suggested different pacing behaviours.
| S-EPMC7386619 | biostudies-literature
Project description:BackgroundIn the last decades, marathon running has become a popular form of physical activity among people around the world. It should be noticed that the main marathon races are performed in large cities, where air quality varies considerably. It is well established that breathing polluted air results in a number of harmful effects to the human body. However, there have been no studies to show the impact of marathon run performance on the amount of the deposition of varied fractions of airborne particulate matter (PM) in the respiratory tract of runners. This is why the present study sought to determine the impact of marathon run performance in the air of varying quality on the deposition of the PM1, PM2.5, PM10 in the respiratory tract in humans.MethodsThe PM1, PM2.5 and PM10 deposition was determined in an "average runner" (with marathon performance time 4 h: 30 min) and in an "elite marathon runner" (with marathon performance time 2 h: 00 min) at rest, and during a marathon race, based on own measurements of the PM content in the air and the size-resolved DF(d) profile concept.ResultsWe have shown that breathing air containing 50 µg m-3 PM10 (a borderline value according to the 2006 WHO standard - still valid) at minute ventilation (VE) equal to 8 L min-1 when at rest, resulted in PM10deposition rate of approximately 9 µg h-1, but a marathon run of an average marathon runner with the VE = 62 L min-1 increased the deposition rate up to 45 µg h-1. In the elite runner, marathon run with the VE= 115 L min-1 increased PM10 deposition rate to 83 µg h-1. Interestingly, breathing the air containing 50 µg m-3of PM10 at the VE = 115 L min-1by the elite marathon runner during the race resulted in the same PM10deposition rate as the breathing highly polluted air containing as much as 466 µg m-3 of PM10 when at rest. Furthermore, the total PM10 deposition in the respiratory tract during a marathon race in average runners is about 22% greater (203 / 166 = 1.22) than in elite runners. According to our calculations, the concentration of PM10in the air during a marathon race that would allow one not to exceed the PM10 deposition rate of 9 µg h-1should be lower than 10 µg m-3 in the case of an average runner, and it should be lower than 5.5 µg m-3 in the case of an elite runner.ConclusionsWe conclude that a marathon run drastically increases the rate of deposition of the airborne PM in the respiratory tract of the runners, as a consequence of the huge VE generated during the race. A decrease of the PM content in the air attenuates this rate. Based on our calculations, we postulate that the PM10 content in the air during a "clean air marathon run", involving elite marathon runners, should be below 5.5 µg m-3.
| S-EPMC8214849 | biostudies-literature
Project description:Among several serious medical conditions, arrhythmia and heat stroke are two important causes of death during endurance races. Clinically, collapsing might be the first sign of these serious conditions and may mimic the more common and benign exercise-associated collapse. Several risk factors have been reported in the literature. We aimed to conduct a qualitative study to find a perceived risk profile among runners who collapsed and who were transported by ambulances to the nearest hospital during Gothenburg's half marathon (2010-2017). Collapsing runners seem to lack the ability to make a decision to withdraw from the contest despite being exhausted. They feel the pain, but are unable to put meaning to their feeling, to adjust their pacing, and to handle other influences. Consequently, they do not overcome the problem or assess the situation. These individual mental characteristics may indicate a unique profile for collapsing runners. Pre-race health control and educational initiatives aiming at mental preparedness and information before endurance races might be a necessary step to avoid life-threatening complications.
| S-EPMC7022577 | biostudies-literature
Project description:BACKGROUND:Investigation into strenuous activity and kidney function has gained interest given increasing marathon participation. STUDY DESIGN:Prospective observational study. SETTING & PARTICIPANTS:Runners participating in the 2015 Hartford Marathon. PREDICTOR:Completing a marathon. OUTCOMES:Acute kidney injury (AKI) as defined by AKI Network (AKIN) criteria. Stage 1 AKI was defined as 1.5- to 2-fold or 0.3-mg/dL increase in serum creatinine level within 48 hours of day 0 and stage 2 was defined as a more than 2- to 3-fold increase in creatinine level. Microscopy score was defined by the number of granular casts and renal tubular epithelial cells. MEASUREMENTS:Samples were collected 24 hours premarathon (day 0), immediately postmarathon (day 1), and 24 hours postmarathon (day 2). Measurements of serum creatinine, creatine kinase, and urine albumin were completed, as well as urine microscopy analysis. 6 injury urine biomarkers (IL-6, IL-8, IL-18, kidney injury molecule 1, neutrophil gelatinase-associated lipocalin, and tumor necrosis factor ?) and 2 repair urine biomarkers (YKL-40 and monocyte chemoattractant protein 1) were measured. RESULTS:22 marathon runners were included. Mean age was 44 years and 41% were men. 82% of runners developed an increase in creatinine level equivalent to AKIN-defined AKI stages 1 and 2. 73% had microscopy diagnoses of tubular injury. Serum creatinine, urine albumin, and injury and repair biomarker levels peaked on day 1 and were significantly elevated compared to day 0 and day 2. Serum creatine kinase levels continued to significantly increase from day 0 to day 2. LIMITATIONS:Small sample size and limited clinical data available at all time points. CONCLUSIONS:Marathon runners developed AKI and urine sediment diagnostic of tubular injury. An increase in injury and repair biomarker levels suggests structural damage to renal tubules occurring after marathon. The results of our study should be validated in larger cohorts with longer follow-up of kidney function.
| S-EPMC5526736 | biostudies-literature