Ontology highlight
ABSTRACT: Background
Brugada syndrome is a disorder associated with sudden cardiac death and characterized by an abnormal electrocardiogram (ECG). Previous studies were predominantly conducted in men, and the data on long-term prognosis are limited. Information about women, especially elderly women, is lacking.Objective
The aim of this study was to investigate the long-term prognosis of the Brugada ECG pattern in elderly women.Method
We investigated the 10-year prognosis of the Brugada ECG pattern in elderly women in a nationwide community-based population in Taiwan. Community-dwelling women older than 55 years were prospectively recruited from December 2008 to March 2013 by a stratified random sampling method. All enrolled individuals were followed up annually until April 2019, and the cause of death was documented by citizen death records.Results
Among 2597 women, 60 (2.31%) had a Brugada-type ECG, and this prevalence was higher than the mean global prevalence of 0.23%. One woman had a type 1 ECG (0.04%), whereas 15 (0.58%) and 44 (1.70%) women had type 2 and type 3 ECG patterns, respectively. Cox survival analysis revealed that all-cause mortality and cardiac mortality were similar in the individuals with and without a Brugada-type ECG during a mean follow-up of 96.1 ± 20.5 months.Conclusions
Our findings suggest that Brugada ECG patterns are not infrequent in elderly women but are not associated with increased risk of mortality in long-term follow-up; these findings may help reduce unnecessary anxiety for physicians, nurses, allied health caregivers, and patients.
SUBMITTER: Yeh SS
PROVIDER: S-EPMC7553189 | biostudies-literature | 2020 Nov/Dec
REPOSITORIES: biostudies-literature
Yeh Sherri Shih-Fan SS Chen Ching-Yu Julius CJ Wu I-Chien IC Hsu Chih-Cheng CC Chen Tzu-Yu TY Tseng Wei-Ting WT Tang Feng-Cheng FC Wang Chi-Chung CC Juan Chung-Chou CC Chiu Hou-Chang HC Lo Huey-Ming HM Yang Dun-Hui DH Juang Jyh-Ming Jimmy JJ Hsiung Chao Agnes CA
The Journal of cardiovascular nursing 20201101 6
<h4>Background</h4>Brugada syndrome is a disorder associated with sudden cardiac death and characterized by an abnormal electrocardiogram (ECG). Previous studies were predominantly conducted in men, and the data on long-term prognosis are limited. Information about women, especially elderly women, is lacking.<h4>Objective</h4>The aim of this study was to investigate the long-term prognosis of the Brugada ECG pattern in elderly women.<h4>Method</h4>We investigated the 10-year prognosis of the Bru ...[more]