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The 10-Year Prognosis and Prevalence of Brugada-Type Electrocardiograms in Elderly Women: A Longitudinal Nationwide Community-Based Prospective Study.


ABSTRACT:

Background

Brugada syndrome is a disorder associated with sudden cardiac death and characterized by an abnormal electrocardiogram (ECG). Previous studies were predominantly conducted in men, and the data on long-term prognosis are limited. Information about women, especially elderly women, is lacking.

Objective

The aim of this study was to investigate the long-term prognosis of the Brugada ECG pattern in elderly women.

Method

We investigated the 10-year prognosis of the Brugada ECG pattern in elderly women in a nationwide community-based population in Taiwan. Community-dwelling women older than 55 years were prospectively recruited from December 2008 to March 2013 by a stratified random sampling method. All enrolled individuals were followed up annually until April 2019, and the cause of death was documented by citizen death records.

Results

Among 2597 women, 60 (2.31%) had a Brugada-type ECG, and this prevalence was higher than the mean global prevalence of 0.23%. One woman had a type 1 ECG (0.04%), whereas 15 (0.58%) and 44 (1.70%) women had type 2 and type 3 ECG patterns, respectively. Cox survival analysis revealed that all-cause mortality and cardiac mortality were similar in the individuals with and without a Brugada-type ECG during a mean follow-up of 96.1 ± 20.5 months.

Conclusions

Our findings suggest that Brugada ECG patterns are not infrequent in elderly women but are not associated with increased risk of mortality in long-term follow-up; these findings may help reduce unnecessary anxiety for physicians, nurses, allied health caregivers, and patients.

SUBMITTER: Yeh SS 

PROVIDER: S-EPMC7553189 | biostudies-literature | 2020 Nov/Dec

REPOSITORIES: biostudies-literature

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Publications

The 10-Year Prognosis and Prevalence of Brugada-Type Electrocardiograms in Elderly Women: A Longitudinal Nationwide Community-Based Prospective Study.

Yeh Sherri Shih-Fan SS   Chen Ching-Yu Julius CJ   Wu I-Chien IC   Hsu Chih-Cheng CC   Chen Tzu-Yu TY   Tseng Wei-Ting WT   Tang Feng-Cheng FC   Wang Chi-Chung CC   Juan Chung-Chou CC   Chiu Hou-Chang HC   Lo Huey-Ming HM   Yang Dun-Hui DH   Juang Jyh-Ming Jimmy JJ   Hsiung Chao Agnes CA  

The Journal of cardiovascular nursing 20201101 6


<h4>Background</h4>Brugada syndrome is a disorder associated with sudden cardiac death and characterized by an abnormal electrocardiogram (ECG). Previous studies were predominantly conducted in men, and the data on long-term prognosis are limited. Information about women, especially elderly women, is lacking.<h4>Objective</h4>The aim of this study was to investigate the long-term prognosis of the Brugada ECG pattern in elderly women.<h4>Method</h4>We investigated the 10-year prognosis of the Bru  ...[more]

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