Ontology highlight
ABSTRACT:
SUBMITTER: Lu H
PROVIDER: S-EPMC7555127 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Lu Huanzi H Dai Wenxiao W Guo Junyi J Wang Dikan D Wen Shuqiong S Yang Lisa L Lin Dongjia D Xie Wenqiang W Wen Liling L Fang Juan J Wang Zhi Z
Frontiers in immunology 20200930
γδ T cells are a small subset of unconventional T cells that are enriched in the mucosal areas, and are responsible for pathogen clearance and maintaining integrity. However, the role of γδ T cells in head and neck squamous cell carcinoma (HNSCC) is largely unknown. Here, by using RNA-seq data from The Cancer Genome Atlas (TCGA), we discovered that HNSCC patients with higher levels of γδ T cells were positively associated with lower clinical stages and better overall survival, and high abundance ...[more]