Ontology highlight
ABSTRACT:
SUBMITTER: Lin W
PROVIDER: S-EPMC7555432 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Frontiers in immunology 20200930
MicroRNAs (miRNAs) play a critical role in various biological processes through regulation of gene expression post-transcriptionally. Although miRNAs are involved in cell proliferation and differentiation in mammals, few reports regarding the effects of host miRNAs on macrophage activation and differentiation are available in birds. Here, we reported that gga-miR-200b-3p acts as a positive regulator, enhancing macrophage activation and differentiation using an avian model. We found that ectopic ...[more]