Ontology highlight
ABSTRACT:
SUBMITTER: Wang Z
PROVIDER: S-EPMC7556049 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Wang Zanxin Z Zhuang Xianmian X Chen Bailang B Wen Junmin J Peng Fang F Liu Xiling X Wei Minxin M
BioMed research international 20201002
<h4>Background</h4>In this study, the whole exome sequencing in human aortic dissection, a highly lethal cardiovascular disease, was investigated to explore the aortic dissection-associated genes and variants in Chinese population.<h4>Methods</h4>Whole exome sequencing was performed in 99 cases of aortic dissection. All single nucleotide polymorphisms (SNPs), insertions/deletions (InDels), and copy number variations (CNVs) were filtered to exclude the benign variants. Enrichment analysis and dis ...[more]