Ontology highlight
ABSTRACT:
SUBMITTER: Carruthers NJ
PROVIDER: S-EPMC7557769 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Carruthers Nicholas J NJ McClellan Sharon A SA Somayajulu Mallika M Pitchaikannu Ahalya A Bessert Denise D Peng Xudong X Huitsing Kylie K Stemmer Paul M PM Hazlett Linda D LD
Pathogens (Basel, Switzerland) 20200918 9
The effects of glycyrrhizin (GLY) on multi-drug resistant (MDR) systemic (MDR9) vs. ocular (B1045) <i>Pseudomonas aeruginosa</i> clinical isolates were determined. Proteomes of each isolate with/without GLY treatment were profiled using liquid chromatography mass spectrometry (LC-MS/MS). The effect of GLY on adherence of MDR isolates to immortalized human (HCET) and mouse (MCEC) corneal epithelial cells, and biofilm and dispersal was tested. Both isolates were treated with GLY (0.25 minimum inhi ...[more]