Ontology highlight
ABSTRACT:
SUBMITTER: Hwang S
PROVIDER: S-EPMC7558343 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Hwang Soyoung S Shin Dong Min DM Hong Jeong Hee JH
Pharmaceutics 20200827 9
IP<sub>3</sub> receptor-binding protein released with IP<sub>3</sub> (IRBIT) interacts with various ion channels and transporters. An electroneutral type of sodium bicarbonate cotransporter, NBCn1, participates in cell migration, and its enhanced expression is related to cancer metastasis. The effect of IRBIT on NBCn1 and its relation to cancer cell migration remain obscure. We therefore aimed to determine the effect of IRBIT on NBCn1 and the regulation of cancer cell migration due to IRBIT-indu ...[more]