Ontology highlight
ABSTRACT:
SUBMITTER: Garcia-Leon JA
PROVIDER: S-EPMC7558359 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Garcia-Leon Juan Antonio JA Caceres-Palomo Laura L Sanchez-Mejias Elisabeth E Mejias-Ortega Marina M Nuñez-Diaz Cristina C Fernandez-Valenzuela Juan Jose JJ Sanchez-Varo Raquel R Davila Jose Carlos JC Vitorica Javier J Gutierrez Antonia A
International journal of molecular sciences 20200918 18
Extracellular amyloid-beta deposition and intraneuronal Tau-laden neurofibrillary tangles are prime features of Alzheimer's disease (AD). The pathology of AD is very complex and still not fully understood, since different neural cell types are involved in the disease. Although neuronal function is clearly deteriorated in AD patients, recently, an increasing number of evidences have pointed towards glial cell dysfunction as one of the main causative phenomena implicated in AD pathogenesis. The co ...[more]