Reduced apparent fiber density in the white matter of premature-born adults.
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ABSTRACT:
SUBMITTER: Menegaux A
PROVIDER: S-EPMC7560721 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Publications
Reduced apparent fiber density in the white matter of premature-born adults.
Menegaux Aurore A Hedderich Dennis M DM Bäuml Josef G JG Manoliu Andrei A Daamen Marcel M Berg Ronja C RC Preibisch Christine C Zimmer Claus C Boecker Henning H Bartmann Peter P Wolke Dieter D Sorg Christian C Stämpfli Philipp P
Scientific reports 20201014 1
Premature-born adults exhibit lasting white matter alterations as demonstrated by widespread reduction in fractional anisotropy (FA) based on diffusion-weighted imaging (DWI). FA reduction, however, is non-specific for microscopic underpinnings such as aberrant myelination or fiber density (FD). Using recent advances in DWI, we tested the hypothesis of reduced FD in premature-born adults and investigated its link with the degree of prematurity and cognition. 73 premature- and 89 mature-born adul ...[more]
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