Ontology highlight
ABSTRACT:
SUBMITTER: Williams OA
PROVIDER: S-EPMC7561018 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Williams Owen A OA An Yang Y Armstrong Nicole M NM Shafer Andrea T AT Helphrey Jessica J Kitner-Triolo Melissa M Ferrucci Luigi L Resnick Susan M SM
Alzheimer's & dementia : the journal of the Alzheimer's Association 20190924 12
<h4>Introduction</h4>Questions remain about whether apolipoprotein E (APOE)-ε4 effects on cognitive decline are similar in men and women and how APOE-ε4 and age interact to influence decline in different cognitive domains.<h4>Methods</h4>In sex-stratified analyses, baseline age-dependent associations between APOE-ε4 status and longitudinal cognitive trajectories were examined in cognitively normal Caucasian older adults (631 men, 561 women, baseline age range: 50-93, 6733 assessments).<h4>Result ...[more]