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Survey report on keratoplasty in China: A 5-year review from 2014 to 2018.

ABSTRACT: To provide the general information on corneal transplantation (CT) in China, China Cornea Society designed a questionnaire on CT from 2014 to 2018 and entrusted it to 31 committee members for implementation of the survey nationwide. This article presents the results of the survey and compares the indicators used in the survey and those in the annual statistical report released by the Eye Bank Association of America (EBAA). The number of corneal transplantations completed by the 64 hospitals from 2014 to 2018 was respectively 5377, 6394, 7595, 8270 and 8980, totally 36,616 (22,959 male and 13,657 female). The five largest hospitals by the number of corneal transplantations completed 15,994 surgeries in total, accounting for 43.68% of all the surgeries performed in the 64 hospitals. The most common indication for corneal transplantations was corneal leukoma (7683, 20.98%), followed by bacterial keratitis (4209, 11.49%), corneal dystrophies (4189, 11.44%), keratoconus (3578, 9.77%) and corneal perforation (2839, 7.75%). The main surgical techniques were penetrating keratoplasty (PK) (19,896, 54.34%), anterior lamellar keratoplasty (ALK) (13,869, 37.88%). The proportion of PK decreased from 57.97% in 2014 to 52.88% in 2018 while the proportion of ALK increased from 36.04% in 2014 to 37.92% in 2018. The geographical distribution of keratoplasties performed in China is unbalanced. PK and ALK were the main techniques of CT and corneal leukoma, bacterial keratitis and corneal dystrophies were the main indications for CT in China.

SUBMITTER: Gao H

PROVIDER: S-EPMC7561196 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature

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Survey report on keratoplasty in China: A 5-year review from 2014 to 2018.

Gao Hua H Huang Ting T Pan Zhiqiang Z Wu Jie J Xu Jianjiang J Hong Jing J Chen Wei W Wu Huping H Kang Qian Q Zhu Lei L Fu Lingling L Wang Liqiang L Li Guigang G Deng Zhihong Z Zhang Hong H Xu Hui H Zhao Qingliang Q Liu Hongshan H Wang Linnong L Chen Baihua B Jin Xiuming X Huang Minghai M Yang Jizhong J Gao Minghong M Zhou Wentian W Xie Hanping H Fu Yao Y Wen Feng F Fu Changbo C Zhao Shaozhen S Yang Yanning Y Fu Yanjiang Y Yao Tao T Wang Chaoqing C Sun Xiaonan X Gao Xiaowei X Reziwan Maimaitiming M Deng Yingping Y Li Jian J Liu Limei L Zeng Bo B Bao Lianyun L Wang Hua H Zhang Lijun L Li Zhiyuan Z Yin Zhijian Z Wen Yuechun Y Zheng Xiao X Du Liqun L Huang Zhenping Z Sheng Xunlun X Zhang Hui H Chen Lizhong L Yan Xiaoming X Liu Xiaowei X Liu Wenhui W Liu Yuan Y Liang Liang L Wu Pengcheng P Qu Lijun L Cheng Jinkui J Zhang Hua H Qi Qige Q Tseten Yangkyi Y Ji Jianping J Yuan Jin J Jie Ying Y Xiang Jun J Huang Yifei Y Yang Yuli Y Li Ying Y Hou Yiyi Y Liu Tong T Xie Lixin L Shi Weiyun W

PloS one 20201015 10

To provide the general information on corneal transplantation (CT) in China, China Cornea Society designed a questionnaire on CT from 2014 to 2018 and entrusted it to 31 committee members for implementation of the survey nationwide. This article presents the results of the survey and compares the indicators used in the survey and those in the annual statistical report released by the Eye Bank Association of America (EBAA). The number of corneal transplantations completed by the 64 hospitals from ...[more]

PMID: 33057425

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Project description:Biogas plants (BGPs) produce methane and carbon dioxide through the anaerobic digestion of agricultural waste. Identification of strategies for more stable biogas plant operation and increased biogas yields require better knowledge about the individual degradation steps and the interactions within the microbial communities. The metaprotein profiles of ten agricultural BGPs and one laboratory reactor were investigated using a metaproteomics pipeline. Fractionation of samples using SDS-PAGE was combined with a high resolution Orbitrap mass spectrometer, metagenome sequences specific for BGPs, and the MetaProteomeAnalyzer software. This enabled us to achieve a high coverage of the metaproteome of the BGP microbial communities. The investigation revealed approx. 17,000 protein groups (metaproteins), covering the majority of the expected metabolic networks of the biogas process such as hydrolysis, transport, fermentation processes, amino acid metabolism, methanogenesis and bacterial C1-metabolism. Biological functions could be linked with the taxonomic composition. Two different types of BGPs were classified by the abundance of the acetoclastic methanogenesis and by abundance of enzymes implicating syntrophic acetate oxidation. Linking of the identified metaproteins with the process steps of the Anaerobic Digestion Model 1 proved the main model assumptions but indicated also some improvements such as considering syntrophic acetate oxidation. Beside the syntrophic interactions, the microbial communities in BGPs are also shaped by competition for substrates and host-phage interactions causing cell lysis. In particular, larger amounts of Bacteriophages for the bacterial families Bacillaceae, Enterobacteriaceae and Clostridiaceae, exceeding the cell number of the Bacteria by approximately four-fold. In contrast, less Bacteriophages were found for Archaea, but more CRISPR proteins were detected. On the one hand, the virus induced turnover of biomass might cause slow degradation of complex biomass in BGP. On the other hand, the lysis of bacterial cells allows cycling of essential nutrients.

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Survey report on keratoplasty in China: A 5-year review from 2014 to 2018.

Publications

Survey report on keratoplasty in China: A 5-year review from 2014 to 2018.

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