Targeting Signaling Pathways in Inflammatory Breast Cancer.
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ABSTRACT:
SUBMITTER: Wang X
PROVIDER: S-EPMC7563157 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Publications
Targeting Signaling Pathways in Inflammatory Breast Cancer.
Wang Xiaoping X Semba Takashi T Phi Lan Thi Hanh LTH Chainitikun Sudpreeda S Iwase Toshiaki T Lim Bora B Ueno Naoto T NT
Cancers 20200901 9
Inflammatory breast cancer (IBC), although rare, is the most aggressive type of breast cancer. Only 2-4% of breast cancer cases are classified as IBC, but-owing to its high rate of metastasis and poor prognosis-8% to 10% of breast cancer-related mortality occur in patients with IBC. Currently, IBC-specific targeted therapies are not available, and there is a critical need for novel therapies derived via understanding novel targets. In this review, we summarize the biological functions of critica ...[more]
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