Ontology highlight
ABSTRACT:
SUBMITTER: Torricelli F
PROVIDER: S-EPMC7563974 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Torricelli Federica F Lococo Filippo F Di Stefano Teresa Severina TS Lorenzini Eugenia E Piana Simonetta S Valli Riccardo R Rena Ottavio O Veronesi Giulia G Billè Andrea A Ciarrocchi Alessia A
Cancers 20200829 9
Malignant Pleural Mesothelioma (MPM) is a heterogeneous disease. Morphologically, three different phenotypes are distinguishable: epithelioid (e-), sarcomatoid (s-) and biphasic (biph-) MPM, the latest, being a mixture of e- and s-MPM cells. Being an intermediate entity, management of biph-MPM, remains debatable and controversial, with different guidelines recommending distinct approaches. Identification of biph-MPM associated genetic alterations, through deep sequencing analysis, may provide us ...[more]