Ontology highlight
ABSTRACT:
SUBMITTER: van der Linden CJ
PROVIDER: S-EPMC7569022 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Cell reports 20201001 1
In mammals, olfactory sensory neurons (OSNs) are born throughout life, ostensibly solely to replace damaged OSNs. During differentiation, each OSN precursor "chooses," out of hundreds of possibilities, a single odorant receptor (OR) gene, which defines the identity of the mature OSN. The relative neurogenesis rates of the hundreds of distinct OSN "subtypes" are thought to be constant, as they are determined by a stochastic process in which each OR is chosen with a fixed probability. Here, using ...[more]