Ontology highlight
ABSTRACT:
SUBMITTER: Semenov VE
PROVIDER: S-EPMC7571187 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Molecules (Basel, Switzerland) 20200912 18
In this study, novel derivatives based on 6-methyluracil and condensed uracil were synthesized, namely, 2,4-quinazoline-2,4-dione with ω-(<i>ortho</i>-nitrilebenzylethylamino) alkyl chains at the N atoms of the pyrimidine ring. In this series of synthesized compounds, the polymethylene chains were varied from having tetra- to hexamethylene chains, and secondary NH, tertiary ethylamino, and quaternary ammonium groups were introduced into the chains. The molecular modeling of the compounds indicat ...[more]