Dataset Information
HaDeX: an R package and web-server for analysis of data from hydrogen-deuterium exchange mass spectrometry experiments.
Ontology highlight
ABSTRACT: Motivation
Hydrogen-deuterium mass spectrometry (HDX-MS) is a rapidly developing technique for monitoring dynamics and interactions of proteins. The development of new devices has to be followed with new software suites addressing emerging standards in data analysis.Results
We propose HaDeX, a novel tool for processing, analysis and visualization of HDX-MS experiments. HaDeX supports a reproducible analytical process, including data exploration, quality control and generation of publication-quality figures.Availability and implementation
HaDeX is available primarily as a web-server (http://mslab-ibb.pl/shiny/HaDeX/), but its all functionalities are also accessible as the R package (https://CRAN.R-project.org/package=HaDeX) and standalone software (https://sourceforge.net/projects/HaDeX/).Supplementary information
Supplementary data are available at Bioinformatics online.
SUBMITTER: Puchala W
PROVIDER: S-EPMC7575049 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Publications
HaDeX: an R package and web-server for analysis of data from hydrogen-deuterium exchange mass spectrometry experiments.
Bioinformatics (Oxford, England) 20200801 16
<h4>Motivation</h4>Hydrogen-deuterium mass spectrometry (HDX-MS) is a rapidly developing technique for monitoring dynamics and interactions of proteins. The development of new devices has to be followed with new software suites addressing emerging standards in data analysis.<h4>Results</h4>We propose HaDeX, a novel tool for processing, analysis and visualization of HDX-MS experiments. HaDeX supports a reproducible analytical process, including data exploration, quality control and generation of ...[more]