Methyl-Coenzyme M Reductase and Its Post-translational Modifications.
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ABSTRACT:
SUBMITTER: Chen H
PROVIDER: S-EPMC7581889 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
Methyl-Coenzyme M Reductase and Its Post-translational Modifications.
Chen Hao H Gan Qinglei Q Fan Chenguang C
Frontiers in microbiology 20201009
The methyl-coenzyme M reductase (MCR) is a central enzyme in anaerobic microbial methane metabolism, which consists of methanogenesis and anaerobic oxidation of methane (AOM). MCR catalyzes the final step of methanogenesis and the first step of AOM to achieve the production and oxidation of methane, respectively. Besides a unique nickel tetrahydrocorphinoid (coenzyme F430), MCR also features several unusual post-translational modifications (PTMs), which are assumed to play important roles in reg ...[more]
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