Ontology highlight
ABSTRACT:
SUBMITTER: Kim SI
PROVIDER: S-EPMC7582493 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Kim Sang-In SI Chaurasiya Shyambabu S Park Anthony K AK Kang Seonah S Lu Jianming J Woo Yanghee Y Yin Hongwei Holly HH Yin Zhirong Z Fong Yuman Y Warner Susanne G SG
International journal of molecular sciences 20201003 19
Oncolytic viroimmunotherapy is an exciting modality that can offer lasting anti-tumor immunity for aggressive malignancies like colon cancer. The impact of oncolytic viruses may be extended by combining them with agents to prime a tumor for viral susceptibility. This study investigates vitamin D analogue as an adjunct to oncolytic viral therapy for colon cancer. While vitamin D (VD) has historically been viewed as anti-viral, our in vitro investigations using human colon cancer cell lines showed ...[more]