Ontology highlight
ABSTRACT:
SUBMITTER: Takheaw N
PROVIDER: S-EPMC7583281 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Takheaw Nuchjira N Pata Supansa S Laopajon Witida W Roytrakul Sittiruk S Kasinrerk Watchara W
BMC research notes 20201022 1
<h4>Objective</h4>CD99, a leukocyte surface molecule, reportedly plays an important role in several cellular processes. However, the role of CD99 in T cell regulation remains unclear, as the CD99 ligand associated with T-cell regulation has not yet been identified. Our previous study showed that recombinant CD99 bound to CD99 ligands was expressed on monocytes, NK cells and dendritic cells. This interaction regulates the expression of IL-6 and TNF-α in CD3 + T cells following T cell activation. ...[more]