Synthesis and characterization of conductive flexible cellulose carbon nanohorn sheets for human tissue applications.

ABSTRACT:

Background

Conductive sheets of cellulose and carbon nanomaterials and its human skin applications are an interesting research aspect as they have potential for applications for skin compatibility. Hence it is needed to explore the effects and shed light on these applications.

Method

To fabricate wearable, portable, flexible, lightweight, inexpensive, and biocompatible composite materials, carbon nanohorns (CNHs) and hydroxyethylcellulose (HEC) were used as precursors to prepare CNH-HEC (Cnh-cel) composite sheets. Cnh-cel sheets were prepared with different loading concentrations of CNHs (10, 20 50,100?mg) in 200?mg cellulose. To fabricate the bio-compatible sheets, a pristine composite of CNHs and HEC was prepared without any pretreatment of the materials.

Results

The obtained sheets possess a conductivity of 1.83?×?10^-?10?S/m and bio-compatible with human skin. Analysis for skin-compatibility was performed for Cnh-cel sheets by h-CLAT in vitro skin sensitization tests to evaluate the activation of THP-1 cells. It was found that THP-1 cells were not activated by Cnh-cel; hence Cnh-cel is a safe biomaterial for human skin. It was also found that the composite allowed only a maximum loading of 100?mg to retain the consistent geometry of free-standing sheets of ConclusionIt can be concluded that cellulose and CNHs sheets are conductive and compatible to human skin applications.

SUBMITTER: Paneer Selvam K 

PROVIDER: S-EPMC7583293 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature