Ontology highlight
ABSTRACT:
SUBMITTER: Lim SM
PROVIDER: S-EPMC7583733 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Lim Seong-Min SM Hwang Juyoung J Park Hae-Bin HB Park Chan Ho CH Jin Jun-O JO
International journal of molecular sciences 20200926 19
(1) Background: Aluminum oxide (Al<sub>2</sub>O<sub>3</sub>) ceramic is one of the materials used for artificial joints, and it has been known that their fine particles (FPs) are provided by the wear of the ceramic. Al<sub>2</sub>O<sub>3</sub> FPs have been shown to induce macrophage activation in vitro; however, the inflammatory effect in vivo has not been studied. (2) Methods: We examined the in vivo effect of Al<sub>2</sub>O<sub>3</sub> FPs on the innate and adaptive immune cells in the mice. ...[more]