Ontology highlight
ABSTRACT:
SUBMITTER: Alekseev A
PROVIDER: S-EPMC7583915 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
International journal of molecular sciences 20201007 19
<i>Deinococcus radiodurans</i> (Dr) has one of the most robust DNA repair systems, which is capable of withstanding extreme doses of ionizing radiation and other sources of DNA damage. DrRecA, a central enzyme of recombinational DNA repair, is essential for extreme radioresistance. In the presence of ATP, DrRecA forms nucleoprotein filaments on DNA, similar to other bacterial RecA and eukaryotic DNA strand exchange proteins. However, DrRecA catalyzes DNA strand exchange in a unique reverse pathw ...[more]