Ontology highlight
ABSTRACT:
SUBMITTER: Hao Q
PROVIDER: S-EPMC7591261 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
eLife 20201027
Cell cycle is a cellular process that is subject to stringent control. In contrast to the wealth of knowledge of proteins controlling the cell cycle, very little is known about the molecular role of lncRNAs (long noncoding RNAs) in cell-cycle progression. By performing genome-wide transcriptome analyses in cell-cycle-synchronized cells, we observed cell-cycle phase-specific induction of >2000 lncRNAs. Further, we demonstrate that an S-phase-upregulated lncRNA, <i>SUNO1</i>, facilitates cell-cycl ...[more]