N-(2-mercaptopropionyl)-glycine enhances in vitro pig embryo production and reduces oxidative stress.
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ABSTRACT:
SUBMITTER: Cambra JM
PROVIDER: S-EPMC7596235 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
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N-(2-mercaptopropionyl)-glycine enhances in vitro pig embryo production and reduces oxidative stress.
Cambra J M JM Martinez C A CA Rodriguez-Martinez H H Martinez E A EA Cuello C C Gil M A MA
Scientific reports 20201029 1
This study evaluated the effects of different concentrations (1, 10, 25, 50, and 100 µM) of the antioxidant N-(2-mercaptopropionyl)-glycine (NMPG), during the culture of in vitro-fertilized porcine oocytes. While the highest concentrations of NMPG (50 and 100 µM) were toxic to the developing embryos during the first two days of culture, 25 µM NMPG achieved cleavage rates that were similar to those achieved by the control but did not sustain blastocyst production by Day 7 of culture. Compared to ...[more]
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