Ontology highlight
ABSTRACT:
SUBMITTER: Tecer D
PROVIDER: S-EPMC7598488 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Tecer Duygu D Gogus Feride F Kalkanci Ayse A Erdogan Merve M Hasanreisoglu Murat M Ergin Çagri Ç Karakan Tarkan T Kozan Ramazan R Coban Seda S Diker Kadir Serdar KS
PloS one 20201030 10
Behçet's Syndrome (BS) is a multisystem vasculitis with various clinical manifestations. Pathogenesis is unclear, but studies have shown genetic factors, innate immunity and autoinflammation to have an important role in the disease course. Diversity in the microbial community of gut microbiota may significantly contribute to the activation of the innate immune system. The clinical features of BS present themselves in clusters and each cluster may be a consequence of different disease mechanisms. ...[more]