Ontology highlight
ABSTRACT:
SUBMITTER: Jia X
PROVIDER: S-EPMC7598782 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Jia Xuemei X Guo Ruitong R Hu Zhenbiao Z Liu Jianxin J Liu Jianping J Li Bolin B Yang Qian Q He Jianming J
Medicine 20201001 44
<h4>Background</h4>Positioning infliximab (IFX), cyclosporine and tacrolimus (TAC) for treating ulcerative colitis (UC) is in great debate.<h4>Methods</h4>A literature search identified studies that investigated IFX vs. cyclosporine or IFX vs TAC in UC patients. Short-term remission, short-term, 1-year and 3-year colectomy rate were employed as primary end-points to assess efficacy. Odds ratios (ORs) with 95% confidence intervals (CIs) were analyzed.<h4>Results</h4>Overall, 15 studies comprised ...[more]