Ontology highlight
ABSTRACT:
SUBMITTER: Parackova Z
PROVIDER: S-EPMC7600406 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Parackova Zuzana Z Zentsova Irena I Bloomfield Marketa M Vrabcova Petra P Smetanova Jitka J Klocperk Adam A Mesežnikov Grigorij G Casas Mendez Luis Fernando LF Vymazal Tomas T Sediva Anna A
Cells 20200929 10
COVID-19, caused by SARS-CoV-2 virus, emerged as a pandemic disease posing a severe threat to global health. To date, sporadic studies have demonstrated that innate immune mechanisms, specifically neutrophilia, NETosis, and neutrophil-associated cytokine responses, are involved in COVID-19 pathogenesis; however, our understanding of the exact nature of this aspect of host-pathogen interaction is limited. Here, we present a detailed dissection of the features and functional profiles of neutrophil ...[more]