Ontology highlight
ABSTRACT:
SUBMITTER: Jarrahi A
PROVIDER: S-EPMC7601301 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Jarrahi Abbas A Braun Molly M Ahluwalia Meenakshi M Gupta Rohan V RV Wilson Michael M Munie Stephanie S Ahluwalia Pankaj P Vender John R JR Vale Fernando L FL Dhandapani Krishnan M KM Vaibhav Kumar K
Biomedicines 20200929 10
Studying the complex molecular mechanisms involved in traumatic brain injury (TBI) is crucial for developing new therapies for TBI. Current treatments for TBI are primarily focused on patient stabilization and symptom mitigation. However, the field lacks defined therapies to prevent cell death, oxidative stress, and inflammatory cascades which lead to chronic pathology. Little can be done to treat the mechanical damage that occurs during the primary insult of a TBI; however, secondary injury mec ...[more]